Key result
PCI fails to restore distal flow in COVID-19 STEMI cases due to extensive thrombosis.
Why the study?
The pathophysiology of STEMI is not well understood in COVID-19.
Case Report (n=2)
No
COVID-19 infection may be associated with a pro-thrombotic state leading to extensive coronary thrombosis and failure to restore distal flow during PCI for STEMI.
May warrant caution during PCI for COVID-19 STEMI; leaves open whether tailored antithrombotic strategies merit prospective evaluation.
The pathophysiology of ST-elevation myocardial infarction (STEMI) is not well understood in Coronavirus disease 2019 (COVID-19). We present similar angiographic findings in two COVID-19 patients with STEMI. Despite percutaneous coronary intervention (PCI), distal coronary flow was not restored. The pro-thrombotic and inflammatory effects of COVID-19 may lead to myocardial infarction.
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Li et al. (2020) conducted a case report in STEMI and COVID-19 (n=2). Percutaneous coronary intervention (PCI) was evaluated on Restoration of distal coronary flow. In two patients with COVID-19 and STEMI, percutaneous coronary intervention failed to restore distal coronary flow due to extensive microvascular and macrovascular thrombosis.
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