Why the study?
Is the presence of negative symptoms associated with a higher prevalence of metabolic syndrome in adult outpatients with schizophrenia?
Population
1,120 adult outpatients with schizophrenia, mean age 46.8 years, 58.4% men.
Comparison
Presence of negative symptoms vs Absence of negative symptoms
Design
Cohort
Key result
The presence of negative symptoms in patients with schizophrenia was associated with a significantly higher prevalence of metabolic syndrome compared to those without (43.9% vs 34.9%, P=0.002; OR 1.6).
Authors
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Negative symptoms associated with higher MetS prevalence in schizophrenia outpatients; hypothesis-generating, warrants prospective confirmation before targeted interventions.
Cohort (n=1,120)
Is the presence of negative symptoms associated with a higher prevalence of metabolic syndrome in adult outpatients with schizophrenia?
Odds Ratio: 1.6
Absolute Event Rate: 43.9% vs 34.9%
p-value: p=0.002
In adult outpatients with schizophrenia, the presence of negative symptoms is significantly associated with a higher prevalence of metabolic syndrome.
Mauriño et al. (2014) conducted a cohort in Schizophrenia (n=1,120). Presence of negative symptoms vs. Absence of negative symptoms was evaluated on Prevalence of metabolic syndrome (MetS) (OR 1.6, p=0.002). The presence of negative symptoms in patients with schizophrenia was associated with a significantly higher prevalence of metabolic syndrome compared to those without (43.9% vs 34.9%, P=0.002; OR 1.6).
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