The infiltration of eosinophils into sites of active inflammation is seen in a number of gastrointestinal diseases. The precise role of the eosinophil in the pathophysiology of these disease processes, however, has not been elucidated. This review discusses some of the gastrointestinal conditions associated with eosinophilia, presents recent evidence regarding the potential mechanisms involved in the recruitment and migration of eosinophils, and discusses the mediators produced by eosinophils that may be involved in the initiation or regulation of the inflammatory response.
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Furuta et al. (1995) studied this question.