Key result
Administration of 0.9% saline in surgical patients frequently leads to hyperchloremia (>20%), which is associated with increased morbidity, length of stay, and mortality compared to balanced fluids.
Why the study?
Does 0.9% saline compared to balanced crystalloid solutions increase the risk of hyperchloremia and worse outcomes in surgical patients?
Does 0.9% saline compared to balanced crystalloid solutions increase the risk of hyperchloremia and worse outcomes in surgical patients?
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This editorial argues against the routine use of 0.9% saline for volume resuscitation in surgical patients due to the risk of hyperchloremia and associated adverse outcomes compared to balanced crystalloids.
Butterworth et al. (2013) conducted an editorial in Surgical patients requiring intravenous fluid therapy. 0.9% saline vs. Balanced crystalloid solutions (e.g., lactated Ringer's solution, Normosol) was evaluated. Administration of 0.9% saline in surgical patients frequently leads to hyperchloremia (>20%), which is associated with increased morbidity, length of stay, and mortality compared to balanced fluids.
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