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From the Department of Surgery, the Division of Surgical Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, OH. For postoperative infections occurring after previous antibiotic therapy, either for prophylaxis or treatment of infection, there is a sufficiently high probability that resistant organisms will be present to warrant initial empirical treatment with agents aimed at multidrug-resistant Gram-negative and Gram-positive organisms.
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Joseph S. Solomkin (2001) studied this question.
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