Key result
OSAHS is linked to decreased right atrial reservoir and conduit strain and increased contraction strain.
Why the study?
This study aimed to assess right atrial function in patients with obstructive sleep apnea hypopnea syndrome using two-dimensional speckle tracking echocardiography.
Does obstructive sleep apnea hypopnea syndrome alter right atrial function and structure as assessed by two-dimensional speckle tracking echocardiography compared to healthy controls?
Case-Control (n=220)
Does obstructive sleep apnea hypopnea syndrome alter right atrial function and structure as assessed by two-dimensional speckle tracking echocardiography compared to healthy controls?
Two-dimensional speckle tracking echocardiography identifies significant structural and functional alterations in the right atrium of patients with OSAHS that correlate with disease severity.
Right atrial strain by 2D-STE may detect subclinical changes in OSAHS; hypothesis-generating, prospective validation needed before clinical use.
Objective This study aimed to unveil the right atrial function in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) using two-dimensional speckle tracking echocardiography (2D-STE).Methods A total of 120 OSAHS patients were enrolled as the OSAHS group, with 100 healthy individuals served as the control group. Conventional echocardiography assessed right atrial structure, including superior-inferior diameter, transverse diameter, area, and volume. Myocardial longitudinal strain parameters (reservoir strain (RASr), conduit strain (RAScd), and contraction strain (RASct)) were measured using 2D-STE. Comparisons were made between groups, and patients were further stratified by apnea-hypopnea index (AHI) into mild (5-14 events/h), moderate (15-39 events/h), and severe (≥ 40 events/h) subgroups. Correlation with AHI was assessed by Pearson correlation analysis.Results Compared to controls, the OSAHS group showed progressive decreases in RASr and RAScd, and increases in RASct and transverse diameter with increasing disease severity (P < 0.05). AHI was negatively correlated with RASr and RAScd, and positively correlated with RASct and transverse diameter (P < 0.05).Conclusion Patients with OSAHS exhibit significant structural and functional alterations of the right atrium. 2D-STE provides a reliable, non-invasive method for early assessment and clinical evaluation of right atrial dysfunction in OSAHS patients.
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Liu et al. (2026) conducted a case-control in Obstructive sleep apnea hypopnea syndrome (n=220). Obstructive sleep apnea hypopnea syndrome vs. Healthy individuals was evaluated on Right atrial function and structure (RASr, RAScd, RASct, and transverse diameter) (p=< 0.05). Obstructive sleep apnea hypopnea syndrome was associated with progressive decreases in right atrial reservoir and conduit strain and increases in contraction strain compared to controls (P < 0.05).
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