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January 1, 1973Archivum histologicum japonicumOpen Access

Endothelial Surface of Rabbit Aorta as Observed by Scanning Electron Microscopy

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Key result

Electron microscopy reveals the rabbit aortic endothelial surface features hair-like projections up to 3 µm long.

Population

Rabbit ascending aorta and arcus aortae

Design

Preclinical

Authors

JTJunichi TokunagaUniversity of California, RiversideMOMichitoshi OSAKAJapanese Red Cross Society, JapanTFTsuneo FujitaHudson Institute

Discussion

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Implication

No immediate clinical implications from rabbit data; leaves open whether analogous endothelial projections exist in humans or influence vascular function.

Structured PICO

P
Population
Adult rabbits whose ascending aorta and aortic arch were examined to observe the endothelial surface structure.
E
Exposure
Scanning and transmission electron microscopy
O
Outcome
Observation of endothelial surface structuresurrogate

The discovery of hair-like projections on the endothelial surface of rabbit aortas suggests a fundamental revision in the understanding of blood vessel endothelial structure.

Limitations

  • Animal model (rabbits) may not perfectly reflect human anatomy
  • Sample size of animals used is not specified

Cite This Study

Tokunaga et al. (1973) studied Normal vascular anatomy. Scanning and transmission electron microscopy was evaluated. Scanning electron microscopy of the rabbit aorta revealed that the endothelial surface possesses numerous hair-like projections up to 3 µm long, challenging the belief that the surface is smooth.

synapsesocial.com/papers/6aa7a4eed40d800ba996eaa3https://doi.org/10.1679/aohc1950.36.129
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Red Pulp of the Rabbit Spleen Studied under the Scanning Electron Microscope1970 · 22 citations
  2. 2Endothelial Projections as Revealed by Scanning Electron Microscopy1971 · 107 citations
  3. 3ENDOTHELIAL CONTRACTION INDUCED BY HISTAMINE-TYPE MEDIATORS1969 · 832 citations