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September 14, 2026MicrosurgeryOpen Access

Pre‐Incision Time Intervals and Outcomes of Free Flap re‐Exploration: A Retrospective Single‐Center Study

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Key result

Pre-incision delays show no association with free-flap salvage failure.

  • P=0.89
  • n=113

Why the study?

Are pre-incision delays associated with free-flap salvage failure in patients undergoing free-flap revision surgery?

Population

113 free-flap revision surgeries performed over the past 6 years at a single center

Design

Cohort

Authors

AFAlexander FiedlerNINesrin IbrahimMFMaria Fueth

Discussion

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Overview

Pre-incision delays may be associated with free-flap salvage failure; supports workflow targets but leaves open prospective validation.

Key Points

  • To determine whether pre-incision delays between surgery registration and incision correlate with free flap salvage failure and identify workflow targets for clinical improvement.
  • Retrospective single-center review of 113 free-flap revision surgeries conducted over 6 years.
  • Partitioned the registration-to-incision pathway into arrival latency, anesthesia lead time, operating room preparation, and surgery lead time to evaluate primary outcomes of salvage versus total flap loss.
  • Total flap loss occurred in 14.2% of re-explorations, with no significant difference in median registration-to-incision time between flap salvage and failure (78 min vs. 77 min, p = 0.89).
  • No significant differences occurred across transit and preparation sub-intervals, including arrival latency (19 min vs. 20 min, p = 0.89), operating room preparation (25 min vs. 22 min, p = 0.66), and door-to-incision duration (52 min vs. 53 min, p = 0.50).
  • Failures trended toward longer anesthesia lead times (38 vs. 28 min, p = 0.48), longer operative durations (109 vs. 83 min, p = 0.12), and weekend procedures (25% vs. 12%, p = 0.06).

Study Design

Type

Cohort (n=113)

Multicenter

No

Structured PICO

Are pre-incision delays associated with free-flap salvage failure in patients undergoing free-flap revision surgery?

P
Population
113 free-flap revision surgeries performed over 6 years to evaluate pre-incision time intervals and outcomes.
E
Exposure
Pre-incision time intervals (arrival latency, anesthesia lead time, operating-room preparation, and surgery lead time)
O
Outcome
Salvage versus failure (total loss)hard clinical

Main Result

p-value: p=0.89

Pre-incision delays were not associated with free-flap salvage failure, suggesting quality improvement should focus on rapid recognition and anesthesia-surgery coordination rather than ward-to-incision logistics.

Cite This Study

Fiedler et al. (2026) conducted a cohort in Free flap vascular compromise (n=113). Pre-incision delays was evaluated on Salvage versus failure (total loss) (p=0.89). Pre-incision delays were not associated with free-flap salvage failure (14.2% total loss rate), with median registration-to-incision times similar between salvage and failure (78 vs 77 min, p=0.89).

synapsesocial.com/papers/6aa7afef79e9260bc85aac93https://doi.org/10.1002/micr.70292
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