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December 20, 2025BMC MicrobiologyOpen Access

Prevalence and antimicrobial resistance of Escherichia coli and Klebsiella spp in dairy farm in the Tigray Region, Northern Ethiopia

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Authors

GGGoyitom Gebremedhn GebruMSMuthupandian Saravanan

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Overview

Cross-sectional study reveals high multidrug resistance in dairy farm Escherichia coli and Klebsiella species, highlighting substantial food safety and public health risks.

Key Points

  • To evaluate the prevalence and antimicrobial resistance profiles of Escherichia coli and Klebsiella species across dairy farm environments in northern Ethiopia.
  • Conducted a cross-sectional study analyzing N=712 total samples (178 each of raw bulk tank milk, milk-container swabs, water, and milkers' stool) between December 2024 and May 2025.
  • Identified isolates via standard culture and biochemical testing, with susceptibility determined using CLSI (2024) disk diffusion and ESBL production confirmed via the double-disk synergy test.
  • Bacterial isolates were detected in 69.4% (494/712) of samples, dominated by E. coli (49.6%), followed by K. pneumoniae (10.3%) and K. oxytoca (9.6%).
  • High resistance occurred against tetracycline (62.9%), amoxicillin/clavulanic acid (31.2%), and trimethoprim-sulfamethoxazole (27.7%), while meropenem resistance remained low at 2.4%.
  • Multidrug resistance was observed in 32.4% of isolates overall (32.0% in E. coli), and extended-spectrum β-lactamase production was confirmed in 10.7% (53/494) of isolates.

Cite This Study

Gebru et al. (2025) studied this question.

synapsesocial.com/papers/6aa7b1ea394eb5723c8da5d9https://doi.org/10.1186/s12866-025-04643-8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Farm‐Level Factors Associated With Multidrug‐Resistant <i>Escherichia coli</i> and <i>Klebsiella</i> spp. in Bulk Tank Milk in Tigray, Northern Ethiopia2026
  2. 2Fecal carriage of carbapenemase-producing Escherichia coli and Klebsiella spp. and associated factors among dairy farm milkers in Tigray Region, Northern Ethiopia2026
  3. 3Antimicrobial resistance of Escherichia coli from dairy cattle farms with different antimicrobial use practices in Ethiopia2026 · 2 citations
  4. 4Multidrug-resistance and extended-spectrum beta-lactamase-producing lactose-fermenting enterobacteriaceae in the human-dairy interface in northwest Ethiopia2024 · 11 citations
  5. 5Antimicrobial resistance and prevalence of extended-spectrum beta-lactamase-producing <i>Klebsiella</i> species in East Tennessee dairy farms2024 · 1 citations