Retrospective contact-tracing analysis reveals significant superspreading dynamics in Andes virus infections, highlighting a nonnegligible risk of large human outbreaks without rodent hosts.
By using historical contact tracing data, we estimated that 23.4% of case-patients caused 80% of Andes virus (ANDV) person-to-person transmission. We demonstrated a low but nonnegligible probability of observing a large-scale ANDV infection outbreak in a rodent-free setting consisting of close contacts, despite the historically self-limited person-to-person transmission of ANDV.
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Guo et al. (2026) studied this question.
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