What does this research mean for the field?

Citric acid is the most effective agent for repassivating titanium surfaces after implantoplasty, providing the optimal combination of high corrosion resistance, minimal ion release, and strong antibacterial effects without cytotoxicity. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the repassivation effects of various chemical disinfectants on titanium surface integrity, corrosion resistance, ion release, cytotoxicity, and bacterial behavior following implantoplasty.

September 14, 2026Dentistry JournalOpen Access

Repassivation of Titanium Surface with Different Disinfectants After Implantoplasty: Effects on Corrosion, Ion Release, Cytotoxicity and Bacterial Behaviour—An In Vitro Study

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Authors

LMLeyre Millas JVJavi VilarrasaUniversitat Internacional de Catalunya NCNeus CarrióUniversitat Internacional de Catalunya

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Implication

In vitro study demonstrates that citric acid restores corrosion resistance and limits ion release on modified titanium surfaces, highlighting an effective protocol for post-implantoplasty care.

Key Points

To evaluate the repassivation effects of various chemical disinfectants on titanium surface integrity, corrosion resistance, ion release, cytotoxicity, and bacterial behavior following implantoplasty.
Treated 128 titanium discs post-implantoplasty with citric acid (CA), ethylenediaminetetraacetic acid (EDTA), hydrogen peroxide (H2O2), or saline control.
Assessed surface topography, wettability, potentiodynamic polarization in Hank's solution, and 21-day titanium ion release via inductively coupled plasma mass spectrometry.
Evaluated cytotoxicity in human fibroblasts and osteoblasts, alongside 24- and 48-hour bacterial adhesion and viability of Streptococcus sanguinis and Pseudomonas aeruginosa.
Hydrogen peroxide increased surface roughness, whereas citric acid and EDTA preserved baseline topography; both citric acid and hydrogen peroxide produced the greatest gains in surface wettability and energy.
Citric acid demonstrated the highest corrosion resistance and lowest cumulative titanium ion release over 21 days without inducing cytotoxic effects in human fibroblast or osteoblast cultures.
All chemical treatments reduced bacterial adhesion relative to control, with citric acid and hydrogen peroxide exhibiting superior bactericidal efficacy against both bacterial strains.

Cite This Study

Millas et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b2e10926e14a848b16f3 https://doi.org/10.3390/dj14090587

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Implication

In vitro study demonstrates that citric acid restores corrosion resistance and limits ion release on modified titanium surfaces, highlighting an effective protocol for post-implantoplasty care.

Repassivation of Titanium Surface with Different Disinfectants After Implantoplasty: Effects on Corrosion, Ion Release, Cytotoxicity and Bacterial Behaviour—An In Vitro Study

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Implication

Key Points

Cite This Study

Repassivation of Titanium Surface with Different Disinfectants After Implantoplasty: Effects on Corrosion, Ion Release, Cytotoxicity and Bacterial Behaviour—An In Vitro Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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