What is the clinical evidence from this study?

Study design: Case Report. Population: Right atrial lipoma (n=1). Intervention: Multimodality imaging and surgical resection.

What does this research mean for the field?

A comprehensive multimodality imaging approach successfully diagnoses right atrial lipoma and facilitates its differentiation from other cardiac tumors. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To present the multimodality imaging characteristics of an incidental right atrial lipoma and evaluate its role in distinguishing benign fatty masses from other cardiac neoplasms.

September 14, 2026MedicineOpen Access

Imaging features of right atrial lipoma on multimodality imaging

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Key result

Multimodality imaging guides successful resection of right atrial lipoma with no recurrence at 9 months.

Why the study?

Cardiac lipomas frequently present with nonspecific or no symptoms and variable morphology, creating a diagnostic challenge.

Population

A 53-year-old asymptomatic female patient with a right atrial mass

Design

Case report

Authors

QXQilong XieBengbu Medical College AFAijuan FangNanjing Drum Tower Hospital XCXinmin ChenNanjing Drum Tower Hospital

Discussion

Member takes

Implication

May support multimodality imaging for incidental right atrial masses; leaves open prospective validation of diagnostic strategies.

Key Points

To present the multimodality imaging characteristics of an incidental right atrial lipoma and evaluate its role in distinguishing benign fatty masses from other cardiac neoplasms.
Evaluated an asymptomatic 53-year-old female presenting with an incidental right atrial mass detected on routine transthoracic echocardiography (TTE).
Characterized the mass using two- and three-dimensional transesophageal echocardiography (TEE), computed tomography (CT), cardiac magnetic resonance (CMR), and 18F-FDG PET-CT.
Performed complete surgical resection with histopathological confirmation and monitored the patient for recurrence over a 9-month follow-up period.
TEE delineated a mobile, pedunculated mass (2.86 cm × 1.62 cm) at the superior vena cava-right atrial junction, mimicking a myxoma, while CT confirmed fat attenuation (16 mm) and CMR demonstrated low signal intensity on T2-weighted fat-suppressed sequences (21 × 10 mm).
PET-CT identified a 1.9 cm × 1.2 cm mass with minimal radiotracer uptake (SUVmax = 1.3), ruling out extracardiac metastases and primary malignant liposarcoma.
Histopathology confirmed a benign cardiac lipoma following complete surgical excision, with no residual mass or tumor recurrence observed during 9 months of follow-up.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 53-year-old asymptomatic female patient with a right atrial lipoma evaluated with multimodality imaging and treated with surgical resection, followed for 9 months.

Intervention

Multimodality imaging (TTE, TEE, CT, PET-CT, CMR) and surgical resection

Outcome

Diagnosis of right atrial lipoma and postoperative recurrence

A comprehensive multimodality imaging approach is crucial for the accurate diagnosis and differentiation of cardiac lipomas from other cardiac masses, guiding successful surgical management.

Cite This Study

Xie et al. (2026) conducted a case report in Right atrial lipoma (n=1). Multimodality imaging and surgical resection was evaluated. A comprehensive multimodality imaging approach successfully diagnosed a right atrial lipoma in an asymptomatic 53-year-old woman, which was completely excised with no recurrence at 9 months.

synapsesocial.com/papers/6aa7b2e10926e14a848b1710 https://doi.org/10.1097/md.0000000000050606

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Imaging features of right atrial lipoma on multimodality imaging

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Imaging features of right atrial lipoma on multimodality imaging

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

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