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September 14, 2026American Journal of Veterinary ResearchOpen Access

Magnetic resonance imaging identifies prognostic features in dogs and cats with ischemic cerebrovascular accidents

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Authors

JDJ DesbordesASAbdelghani SifouaneYRYannick Ruel

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Overview

Retrospective observational study reveals that extensive infarcts with mass effect predict early mortality in dogs and cats, indicating key prognostic value of brain MRI.

Key Points

  • To characterize MRI and arterial spin labeling perfusion features in dogs and cats with ischemic cerebrovascular accidents and identify imaging findings linked to clinical prognosis.
  • Retrospective, single-center observational study of 63 companion animals (47 dogs and 16 cats) presenting with acute, nonprogressive brain dysfunction from 2018 through 2024.
  • Evaluated brain MRI protocols including arterial spin labeling perfusion imaging to classify ischemic cerebrovascular accident subtypes and assess clinical outcomes.
  • A complete territorial infarct subtype was identified in 8 of 63 animals (12.7%) and was frequently accompanied by moderate-to-severe mass effect.
  • Malignant ischemic cerebrovascular accidents—defined by complete territorial involvement with moderate-to-severe mass effect—were strongly associated with early mortality (OR, 400; 95% CI, 14.5 to 11,039).
  • All nonlacunar infarcts demonstrated focal arterial spin labeling hypoperfusion, whereas lacunar infarcts showed no perfusion defects, and ischemic penumbra was detected in only 2 of 19 animals (10.5%) scanned within 24 hours of onset.

Cite This Study

Desbordes et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b2e10926e14a848b1746https://doi.org/10.2460/ajvr.26.06.0268
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  5. 5Complete blood count-derived inflammatory markers in canine cerebrovascular accidents: diagnostic utility and prognostic implications2026