Answers are grounded in this paper and cite their sources.
Experimental study demonstrates efficient synthesis of polysubstituted fluoroalkylalkenes using photoredox/copper dual catalysis, highlighting broad functional group tolerance.
Herein, we have developed photoredox/copper dual catalysis for the synthesis of structurally useful polysubstituted fluoroalkylalkenes. The cascade reaction involves defluoronative difluoroalkyl radical formation, radical addition to vinylene carbonate, radical-metal binding, β-elimination, and decarboxylation. This approach efficiently affords stereoregular tri- and tetrasubstituted fluoroalkyl alkenes with broad functional group tolerance.
No takes yet. Share an insight, caveat, or question.
Zhu et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: