What does this research mean for the field?

Zoom-DWI provides superior tumor margin visualization in gastric cancer compared to General-DWI, but yields systematically lower apparent diffusion coefficient (ADC) measurements, making it unsuitable for quantitative assessments that rely on established ADC thresholds. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate and compare image quality, apparent diffusion coefficient (ADC) values, and entropy metrics derived from Zoom-DWI versus General-DWI in patients with gastric cancer.

September 14, 2026BMC Medical ImagingOpen Access

Zoom-DWI versus general-DWI in gastric cancer: a comparative evaluation of image quality, apparent diffusion coefficient, and entropy

View Full Paper

Ask AI

Bookmark

Authors

HXHuan Xie HWHanwei Wang ZCZhile Cao

Discussion

Member takes

Overview

Retrospective study demonstrates Zoom-DWI improves tumor boundary visualization but underestimates ADC in gastric cancer, indicating it cannot replace general-DWI for standardized quantitative...

Key Points

To evaluate and compare image quality, apparent diffusion coefficient (ADC) values, and entropy metrics derived from Zoom-DWI versus General-DWI in patients with gastric cancer.
Single-center retrospective study evaluating 70 patients with histopathologically confirmed gastric cancer who underwent abdominal MRI between March 2023 and October 2024.
Free-breathing, 2D fat-suppressed Zoom-DWI and General-DWI sequences were analyzed for qualitative image quality and quantitative tumor ADC and entropy values.
Statistical comparisons included paired t-tests, linear mixed-effects models, Pearson correlation coefficients, and Bland–Altman agreement analysis.
Zoom-DWI demonstrated significantly higher tumor boundary delineation scores (3.78 ± 0.77 vs. General-DWI, P < 0.001) but showed worse image noise performance (3.76 ± 0.91, P = 0.019).
General-DWI yielded significantly higher ADC values than Zoom-DWI [(1.43 ± 0.26) × 10⁻³ mm²/s vs. (1.33 ± 0.25) × 10⁻³ mm²/s, P < 0.001], with linear mixed-effects modeling indicating a systematic Zoom-DWI underestimation bias of −0.096 × 10⁻³ mm²/s.
Mean entropy was 4.70 ± 0.73 for Zoom-DWI compared to 4.72 ± 0.68 for General-DWI (P = 0.701), with strong correlations across sequences (ADC R = 0.906; entropy R = 0.776) but persistent systematic deviation on Bland–Altman analysis.

Cite This Study

Xie et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b3060926e14a848b1be0 https://doi.org/10.1186/s12880-026-02766-6

View Full Paper

Ask AI

Bookmark

September 14, 2026BMC Medical ImagingOpen Access

Zoom-DWI versus general-DWI in gastric cancer: a comparative evaluation of image quality, apparent diffusion coefficient, and entropy

View Full Paper

Ask AI

Bookmark

Authors

HXHuan Xie HWHanwei Wang ZCZhile Cao

Discussion

Member takes

Overview

Retrospective study demonstrates Zoom-DWI improves tumor boundary visualization but underestimates ADC in gastric cancer, indicating it cannot replace general-DWI for standardized quantitative...

Key Points

To evaluate and compare image quality, apparent diffusion coefficient (ADC) values, and entropy metrics derived from Zoom-DWI versus General-DWI in patients with gastric cancer.
Single-center retrospective study evaluating 70 patients with histopathologically confirmed gastric cancer who underwent abdominal MRI between March 2023 and October 2024.
Free-breathing, 2D fat-suppressed Zoom-DWI and General-DWI sequences were analyzed for qualitative image quality and quantitative tumor ADC and entropy values.
Statistical comparisons included paired t-tests, linear mixed-effects models, Pearson correlation coefficients, and Bland–Altman agreement analysis.
Zoom-DWI demonstrated significantly higher tumor boundary delineation scores (3.78 ± 0.77 vs. General-DWI, P < 0.001) but showed worse image noise performance (3.76 ± 0.91, P = 0.019).
General-DWI yielded significantly higher ADC values than Zoom-DWI [(1.43 ± 0.26) × 10⁻³ mm²/s vs. (1.33 ± 0.25) × 10⁻³ mm²/s, P < 0.001], with linear mixed-effects modeling indicating a systematic Zoom-DWI underestimation bias of −0.096 × 10⁻³ mm²/s.
Mean entropy was 4.70 ± 0.73 for Zoom-DWI compared to 4.72 ± 0.68 for General-DWI (P = 0.701), with strong correlations across sequences (ADC R = 0.906; entropy R = 0.776) but persistent systematic deviation on Bland–Altman analysis.

Cite This Study

Xie et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b3060926e14a848b1be0 https://doi.org/10.1186/s12880-026-02766-6

View Full Paper

Ask AI

Bookmark