What does this research mean for the field?

Prodromal sensory disturbance and oral ulceration can precede tongue necrosis as a rare manifestation of giant cell arteritis, particularly in patients with co-existing systemic vasculopathy. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To document an atypical presentation of tongue necrosis secondary to giant cell arteritis in a patient with confounding pre-existing connective tissue disease and vasculopathy.

September 14, 2026Advances in Oral and Maxillofacial SurgeryOpen Access

Tongue necrosis as a rare manifestation of giant cell arteritis in the context of systemic vasculopathy: a case report

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Authors

LVLakshmi Venkatakrishnan ASAlisha SagarSouthampton General Hospital RSRabindra P. Singh

Discussion

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Implication

Case report reports tongue necrosis caused by giant cell arteritis in a patient with systemic vasculopathy, highlighting the necessity of prompt recognition and high-dose corticosteroid therapy.

Key Points

To document an atypical presentation of tongue necrosis secondary to giant cell arteritis in a patient with confounding pre-existing connective tissue disease and vasculopathy.
Clinical and diagnostic evaluation of a 76-year-old woman presenting with progressive oral symptoms and subsequent tongue necrosis (N=1).
Multidisciplinary rheumatologic and surgical intervention involving high-dose systemic corticosteroids and staged surgical debridement.
A prodrome of tongue pain, paresthesia, oral ulceration, and dysphagia progressed to extensive ischemic tongue necrosis over two weeks.
The clinical diagnosis of giant cell arteritis was established despite diagnostic overlap with pre-existing scleroderma, Raynaud's phenomenon, and carotid stenosis, with tissue loss successfully arrested by corticosteroid therapy and surgical debridement.

Cite This Study

Venkatakrishnan et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b31b0926e14a848b1ca2 https://doi.org/10.1016/j.adoms.2026.100722

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Implication

Case report reports tongue necrosis caused by giant cell arteritis in a patient with systemic vasculopathy, highlighting the necessity of prompt recognition and high-dose corticosteroid therapy.

Tongue necrosis as a rare manifestation of giant cell arteritis in the context of systemic vasculopathy: a case report

Discussion

Member takes

Implication

Key Points

Cite This Study

Tongue necrosis as a rare manifestation of giant cell arteritis in the context of systemic vasculopathy: a case report

Discussion

Member takes

Implication

Key Points

Cite This Study

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