LC ‐ OCT of lichen planus pigmentosus: A case series with histopathological correlation

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To evaluate the line-field confocal optical coherence tomography (LC-OCT) features of lichen planus pigmentosus and assess their correlation with histopathological findings.
Conducted a case series imaging cutaneous lesions in patients with lichen planus pigmentosus using line-field confocal optical coherence tomography (LC-OCT).
Performed paired histopathological analysis on skin biopsies to determine microscopic correlation with LC-OCT imaging features.
Demonstrated cellular-level concordance between LC-OCT imaging characteristics and classic histopathological hallmarks of lichen planus pigmentosus.
Identified epidermal and dermal pigmentary changes noninvasively that directly mirrored findings on conventional tissue biopsy.

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Case series demonstrates histopathological correlation of LC-OCT in lichen planus pigmentosus, indicating its utility for noninvasive diagnosis.

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Dimarco et al. (2026) studied this question.

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