Synsepalum dulcificum and its potential use as a source of bioactive molecules in cosmetics

Introduction: Synsepalum dulcificum (miracle fruit) is notable for its ability to transform sour tastes into sweet ones through the glycoprotein miraculin. Although its interaction with taste receptors is its most studied feature, the plant contains other biomolecules in its leaves and seeds with therapeutic potential that extends beyond the food sector. Methodology: A systematic literature review was conducted in high-impact scientific databases, with a primary focus on PubMed, Google Scholar and Uniprot. The search strategy centered on the phytochemical characterization of the species, prioritizing studies on extracts and biomolecules with biological properties suitable for topical and dermatological applications. Results: The research reveals that the berry (skin and pulp) and leaves of S. dulcificum are rich in antioxidant and anti-inflammatory compounds. Additionally, it was determined that the oil extracted from its seeds possesses notable moisturizing properties, positioning the plant as a versatile source of bioactive ingredients. Conclusions: S. dulcificum is a promising resource for the cosmetic and healthcare industries. Its potential as a sugar substitute and source of active ingredients for the skin, scalp, and hair opens new opportunities for scientific research focused on the development of topical products.