What does this research mean for the field?

Socioeconomic deprivation is associated with significantly reduced odds of receiving surgery and chemotherapy, as well as modestly longer diagnostic and treatment intervals, among colon cancer patients in England's universal healthcare system. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To examine socioeconomic inequalities in treatment receipt as well as diagnostic and treatment intervals among individuals diagnosed with colon cancer.

September 14, 2026Cancer EpidemiologyOpen Access

Are there inequalities in colon cancer diagnosis and treatment in England? A population-based study

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Authors

BPBenjamin Pickwell‐SmithUniversity of Leeds LPLewis W. PatonHull York Medical School ISIreneous SoyiriUniversity of Hull

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Implication

Randomized trial demonstrates lower treatment receipt and longer diagnostic delays in socioeconomically deprived colon cancer patients, highlighting persistent healthcare disparities.

Key Points

To examine socioeconomic inequalities in treatment receipt as well as diagnostic and treatment intervals among individuals diagnosed with colon cancer.
Interventional registry-based study (ClinicalTrials.gov NCT05185388) evaluating patients diagnosed with colon cancer in England between 2016 and 2017.
Linked National Cancer Registry Data with Hospital Episode Statistics, Cancer Pathway, Systemic Anti-Cancer Dataset, and Diagnostic Imaging Dataset, measuring deprivation via quintiles of the Index of Multiple Deprivation.
Used multivariable logistic regression to analyze receipt of surgery and chemotherapy, alongside quantile regression to evaluate diagnostic and treatment intervals.
Patients in the most deprived quintile had lower odds of receiving surgical resection compared to those in the least deprived quintile (OR 0.62, 95% CI 0.56–0.69).
Socioeconomic deprivation was associated with reduced receipt of adjuvant chemotherapy for stage II–III disease (OR 0.73, 95% CI 0.65–0.83) and chemotherapy for stage IV disease (OR 0.63, 95% CI 0.54–0.74).
Diagnostic and treatment intervals were 2 to 5 days longer at the median and upper quartiles for patients living in more deprived areas.

Cite This Study

Pickwell‐Smith et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b3df0926e14a848b32df https://doi.org/10.1016/j.canep.2026.103230

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Implication

Randomized trial demonstrates lower treatment receipt and longer diagnostic delays in socioeconomically deprived colon cancer patients, highlighting persistent healthcare disparities.

Are there inequalities in colon cancer diagnosis and treatment in England? A population-based study

Discussion

Member takes

Implication

Key Points

Cite This Study

Are there inequalities in colon cancer diagnosis and treatment in England? A population-based study

Discussion

Member takes

Implication

Key Points

Cite This Study

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