Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
September 14, 2026Journal of Child and Adolescent Psychopharmacology

Systematic Literature Review on Public Health Impacts of Tourette Syndrome and Persistent Tic Disorders: General Health, Health Conditions, and Health Behaviors

View Full Paper
Ask AI
Bookmark
Share

Authors

PWPatricia L WhalenRLRebecca T. LeebHHHelena J. Hutchins

Discussion

Loading...

Member takes

Overview

Systematic review reveals elevated risks of physical comorbidities and lower quality of life in individuals with Tourette syndrome, highlighting the necessity of comprehensive medical care.

Key Points

  • To summarize associations between Tourette syndrome and persistent tic disorders across the lifespan with physical health indicators, general health conditions, and health behaviors.
  • Systematic review of multiple databases through March 5, 2025, identifying 84 comparative studies published in English in 2003 or later.
  • Evaluated physical health outcomes, health behaviors, and health-related quality of life between individuals with and without tic disorders.
  • Assessed risk of bias across included studies using the Newcastle-Ottawa Scale.
  • Individuals with tic disorders exhibited lower health-related quality of life, greater overall disability, higher mortality, and increased rates of injuries and suicidal behaviors.
  • Higher prevalence was observed for orthopedic, neurological, sleep, endocrine, immune-related, and sensory disorders, whereas body mass index and health behaviors showed no difference.
  • Evidence regarding gastrointestinal, circulatory, and infectious conditions remained inconsistent across the evaluated literature.

Cite This Study

Whalen et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b3ee0926e14a848b34adhttps://doi.org/10.1177/10445463261484867
View Full Paper
Ask AI
Bookmark
Share