What does this research mean for the field?

Maternal atopic dermatitis is associated with a modestly increased risk of adverse pregnancy outcomes, including premature rupture of membranes, gestational hypertension, pre-eclampsia, and neonatal Staphylococcal septicaemia. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the association between maternal atopic dermatitis and adverse maternal and neonatal outcomes during pregnancy.

September 14, 2026Journal of the European Academy of Dermatology and Venereology

Adverse pregnancy outcomes in women with atopic dermatitis: A systematic review and meta‐analysis

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Authors

WLW J LiuChang Gung Memorial Hospital ECElisa ChenChang Gung Memorial Hospital CTCheng‐Chen TaiChang Gung Memorial Hospital

Discussion

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Implication

Meta-analysis reveals increased risks of hypertensive disorders and adverse neonatal outcomes in pregnant women with atopic dermatitis, highlighting the need for multidisciplinary monitoring.

Key Points

To evaluate the association between maternal atopic dermatitis and adverse maternal and neonatal outcomes during pregnancy.
Searched MEDLINE, Embase, and CENTRAL through September 7, 2025, for cohort studies assessing atopic dermatitis and pregnancy outcomes.
Evaluated 8 cohort studies covering 278,671 women with atopic dermatitis and over 2,738,216 controls using Newcastle–Ottawa Scale risk-of-bias assessments and random-effects meta-analyses.
Maternal atopic dermatitis was linked to higher odds of premature rupture of membranes (pooled OR 1.16, 95% CI 1.09–1.24) and low birth weight under 2500 g (pooled OR 1.11, 95% CI 1.02–1.20).
Maternal atopic dermatitis correlated with increased risks of gestational hypertension (pooled OR 1.15, 95% CI 1.02–1.29) and pre-eclampsia or eclampsia (pooled OR 1.11, 95% CI 1.03–1.19).
Data from a single cohort indicated a marked increase in neonatal septicaemia caused by Staphylococcal species (OR 2.45, 95% CI 1.33–4.49).

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b41e0926e14a848b3ade https://doi.org/10.1111/jdv.70738

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Implication

Meta-analysis reveals increased risks of hypertensive disorders and adverse neonatal outcomes in pregnant women with atopic dermatitis, highlighting the need for multidisciplinary monitoring.

Adverse pregnancy outcomes in women with atopic dermatitis: A systematic review and meta‐analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Adverse pregnancy outcomes in women with atopic dermatitis: A systematic review and meta‐analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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