Key result
Urgent resection of a cardiac leiomyosarcoma causing LVOT obstruction proves incomplete and fatal at 89 days.
Case Report (n=1)
No
This is the first reported case of primary cardiac leiomyosarcoma causing both mitral stenosis and left ventricular outflow tract obstruction.
Emphasizes lethal course despite urgent resection in this first dual-obstruction case; leaves open optimal management for primary cardiac leiomyosarcoma.
We report a 73-year-old woman with primary cardiac leiomyosarcoma in the left atrium and ventricle. The tumor progressed very rapidly for 2 months after initial clinical evaluation. Obstruction of the left ventricular outflow tract and mitral stenosis were induced by the tumor. Urgent surgical resection was performed because she had cardiogenic shock due to paroxysmal atrial fibrillation. We could not resect the tumor completely because of severe invasion. She refused postoperative chemotherapy and radiotherapy, and died suddenly at home 89 days after surgery. To our knowledge, this is the first observation of mitral stenosis concomitant with obstruction of the left ventricular outflow tract in a patient with primary cardiac leiomyosarcoma.
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Ogimoto et al. (2003) conducted a case report in Primary cardiac leiomyosarcoma (n=1). Urgent surgical resection was evaluated on Clinical outcome / Survival. Urgent surgical resection of a rapidly progressing primary cardiac leiomyosarcoma causing left ventricular outflow tract obstruction and mitral stenosis was incomplete, and the patient died 89 days postoperatively.
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