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November 3, 2016Orphanet Journal of Rare DiseasesOpen Access

Sporadic inclusion body myositis is associated with a ~56-month diagnostic delay and widespread psychological anxiety.

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Why the study?

Sporadic inclusion body myositis is an intractable, progressive muscle disease of unknown etiology without effective treatment, and its cross-sectional profile in Japan needed elucidation.

Population

146 patients diagnosed with sIBM across Japan

Design

Multicenter cross-sectional questionnaire survey

Key result

In a cross-sectional survey of Japanese patients with sporadic inclusion body myositis, the mean time from onset to diagnosis was 55.5 months, with 73% of patients reporting psychological anxiety.

Authors

NSNaoki SuzukiMMMadoka Mori‐YoshimuraSYSatoshi Yamashita

Discussion

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Member takes

Overview

Diagnostic delays and burdens in sporadic inclusion body myositis merit clinical vigilance; leaves open optimal strategies for earlier recognition in rare myopathies.

Study Design

Type

Cross-Sectional (n=146)

Multicenter

Yes

Structured PICO

P
Population
146 patients with definite or probable sporadic inclusion body myositis in Japan, evaluated cross-sectionally to describe clinical profiles, diagnostic delays, and natural history.
O
Outcome
Cross-sectional profile of patients affected by sIBM, including natural history, psychological/mental aspects, and financial management.patient reported

Patients with sporadic inclusion body myositis in Japan experience significant diagnostic delays and high rates of psychological and financial anxiety.

Limitations

  • Retrospective and cross-sectional design cannot determine causal relationships
  • Lack of detailed questions on the functional ability to swallow and the form of consumed food in the questionnaire

Cite This Study

Suzuki et al. (2016) conducted a cross-sectional in Sporadic inclusion body myositis (sIBM) (n=146). Sporadic inclusion body myositis (sIBM) was evaluated on Cross-sectional clinical profile, diagnostic delay, and patient-reported anxiety. In a cross-sectional survey of Japanese patients with sporadic inclusion body myositis, the mean time from onset to diagnosis was 55.5 months, with 73% of patients reporting psychological anxiety.

synapsesocial.com/papers/6aa7c3eadafa71edbfae595fhttps://doi.org/10.1186/s13023-016-0524-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1[Sporadic Inclusion Body Myositis].2024
  2. 2Quantitative muscle MRI in sporadic inclusion body myositis (sIBM): A prospective cohort study2024 · 4 citations
  3. 3Intramyocardial fatty infiltration lesion in sporadic inclusion body myositis: a case report2024
  4. 4Inclusion Body Myositis2024 · 5 citations
  5. 5Clinical and Electrophysiological Findings in Hereditary Inclusion Body Myopathy Compared With Sporadic Inclusion Body Myositis2016 · 16 citations