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This study is the first to characterize ventral hippocampal CA1 physiological firing types in associative fear learning. Distinct intrinsic excitability changes among these populations suggest they contribute uniquely to trace and context fear memory. These findings have important implications for anxiety disorders that depend on the ventral hippocampus and pave the way for future studies to examine how these populations might coordinate with the larger ventral hippocampal network in forming fear associations.
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Ehlers et al. (2025) studied this question.
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