Physiological Scaffold Remodeling in the Coronary Artery After 30 Months of Bioadaptor Implantation

Figures

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  Figure 1. Imaging of the Left Anterior Descending Coronary Artery (A) Initial coronary angiography: Diagnostic coronary angiography shows significant stenosis in the mid-left anterior descending artery. (B) Final coronary angiography: Final angiography after percutaneous coronary intervention shows excellent dilatation of the stenotic lesion using the DynamX Bioadaptor (Elixir Medical Corporation). (C) Cross-sectional area of scaffold: The mean cross-sectional area of the scaffold at every 1 mm over its entire length after 30 months is significantly larger than that immediately after percutaneous coronary intervention (6.99 ± 0.54 mm2 vs 6.73 ± 0.26 mm2; P = 0.044). (D) Intravascular ultrasound findings: Findings at the proximal segment after the index procedure and those at 30 months indicate that the device lumen has become larger and the amount of atherosclerotic plaque outside the scaffold has reduced, compared with the initial amount.

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  Figure 2. Imaging of the Right Coronary Artery (A) Initial coronary angiography: Diagnostic coronary angiography shows significant stenosis in the proximal right coronary artery. (B) Final coronary angiography: Final angiography performed after the percutaneous coronary intervention demonstrates excellent dilatation of the stenotic lesion using the scaffold. (C) Follow-up coronary angiography: The 36-month follow-up angiography indicates narrowing in the proximal part of the scaffold. (D) Cross-sectional area of scaffold: The mean device cross-sectional area is 8.91 ± 1.26 mm2 immediately after percutaneous coronary intervention and 9.81 ± 1.23 mm2 after 36 months (P < 0.001). (E) Optical coherence tomography image in stenosis: At the 36-month follow-up, the cross-sectional area of the scaffold over the lesion with neointimal hyperplasia, with a length of 5 mm has increased compared with the initial value.