Key result
A proposed new definition of exercise pulmonary hypertension requiring both mPAP >30 mmHg and TPR >3 Wood units during maximal exercise may reduce false-positive diagnoses in healthy subjects.
Why the study?
Does a new definition of exercise pulmonary hypertension incorporating total pulmonary resistance reduce false-positive diagnoses compared to using mPAP alone?
Does a new definition of exercise pulmonary hypertension incorporating total pulmonary resistance reduce false-positive diagnoses compared to using mPAP alone?
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Adding total pulmonary resistance >3 Wood units to mPAP >30 mmHg during maximal exercise improves the diagnostic accuracy of exercise pulmonary hypertension by reducing false positives.
Kovács et al. (2016) conducted an editorial in Exercise pulmonary hypertension. New definition of exercise pulmonary hypertension (mPAP >30 mmHg and TPR >3 WU) vs. Old definition (mPAP >30 mmHg alone) was evaluated on False positive exercise-PH diagnoses. A proposed new definition of exercise pulmonary hypertension requiring both mPAP >30 mmHg and TPR >3 Wood units during maximal exercise may reduce false-positive diagnoses in healthy subjects.
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