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Summary There was a significant rise in the human growth hormone response to intravenous thyrotropin releasing hormone in 5 of 10 chronic schizophrenic adolescents maintained on antipsychotic agents, but in none of 10 age and sex matched control subjects. In 4 of the 5 patients with growth hormone rise there was a positive family history of schizophrenia, but such a family history was obtained in only one of the non-responding schizophrenics.
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Weizman et al. (1982) studied this question.
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