A Study of 100 Cases of Arrhythmias in First Week of Acute Myocardial Infarction (AMI) in Gujarat: A High Risk and Previously Undocumented Population.

AIM: To study the incidence of arrhythmias in the first week of Acute Myocardial Infarction (AMI) with respect to type of arrhythmia, age distribution, sex and location of infarctin a patient population from western India and to evaluate its prognostic value and assessment of effect of pharmacotherapy. STUDY DESIGN: A prospective clinical study consisting of 100 patients was undertaken to investigate the relationship of arrhythmia with site of AMI, timing, complications and outcome in terms of mortality and morbidity. MATERIALS AND METHODS: Hundred consecutive cases of AMI with arrhythmia admitted in ICCU of Sir Sayaji General Hospital, Vadodara were taken in the study. RESULTS: Among 100 cases, maximum incidence (41%) was found after 6th decade. Incidence of arrhythmias was higher in males (70%) than females (30%). Anterior wall infarcts (69%) were more common than inferior wall (26%). Ventricular Premature Contraction (VPC) (36.23%) was the commonest arrhythmia is anterior wall MI while Complete Heart Block (CHB) (26.92%) was most frequent in inferior wall MI. A large number of arrhythmias were terminated pharmacologically (39%) whereas 13 % of the arrhythmias persisted in spite of treatment. CONCLUSION: Hence, in one of the largest study of this kind in a patient population of Western India, we established VPC's as the most common arrhythmia in AMI patients. Older patients (sixth decade) and males are affected more commonly. Ventricular tachycardia is more fatal in acute inferior wall MI. Pharmacotherapy was successful in a large number of cases.