Key result
RFA achieves ~95% effectiveness in children aged 0-7, with recurrences linked to ablation parameters.
Why the study?
RFA in young children is limited by the risk of complications and unstudied remote effects of radiofrequency lesions.
Does radiofrequency ablation effectively and safely treat arrhythmias in children aged 0 to 7 years?
Observational (n=209)
Does radiofrequency ablation effectively and safely treat arrhythmias in children aged 0 to 7 years?
Odds Ratio: 0.894 (95% CI 0.804–0.994)
p-value: p=0.039
In preschool children, radiofrequency ablation is highly effective for treating arrhythmias, but reducing maximum power to avoid complications increases the risk of recurrence.
May support RFA consideration in young children; hypothesis-generating for parameter optimization to reduce recurrence.
Background Radiofrequency ablation (RFA) is the standard method of treatment for tachyarrhythmias in school children, and it leads to complete recovery in children without structural heart disease. However, RFA in young children is limited by the risk of complications and unstudied remote effects of radiofrequency lesions. Objective To present the experience of RFA of arrhythmias and the results of follow‐up of younger children. Materials and Methods RFA procedures (n = 255) were performed in 209 children with arrhythmias from 0 to 7 years old. The arrhythmias were presented with atrioventricular reentry tachycardia with Wolff‐Parkinson‐White (WPW) syndrome (56%), atrial ectopic tachycardia (21.5%), atrioventricular nodal reentry tachycardia (4.8%), and ventricular arrhythmia (17.2%). Results The overall effectiveness of RFA, considering the repeated procedures performed due to the primary ineffectiveness and recurrencies, was 94.7%. There was no mortality associated with RFA in patients, including young patients. All cases of “major” complications are associated with RFA of the left‐sided accessory pathway and tachycardia foci and are represented by the mitral valve damage in three patients (1.4%). Tachycardia and preexcitation recurred in 44 (21%) patients. There was a correlation between recurrences and parameters of RFA (odds ratio 0.894; 95% confidence interval: 0.804–0.994; p = .039). Reducing the maximum power of effective applications in our study increased the risk of recurrence. Conclusion The use of the minimum effective parameters of RFA in children reduces the risk of complications, but increases arrhythmia recurrence rate.
No takes yet. Share an insight, caveat, or question.
Свинцова et al. (2023) conducted an observational in Arrhythmias (n=209). Radiofrequency ablation was evaluated on Recurrences (OR 0.894, 95% CI 0.804-0.994, p=0.039). Radiofrequency ablation in children aged 0 to 7 years achieved 94.7% overall effectiveness, with a 21% recurrence rate that correlated with RFA parameters (OR 0.894; 95% CI 0.804-0.994; p=0.039).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: