Key result
Combined olive leaf, green coffee bean, and beetroot extracts fail to lower 24-hour ABP versus placebo.
Why the study?
Does a combined extract of olive leaf, green coffee bean, and beetroot reduce blood pressure in adults with untreated high normal or borderline elevated blood pressure?
Population
37 overweight middle-aged men and women with untreated high normal or borderline elevated blood pressure
Comparison
Active supplement comprising 500 mg olive leaf… vs Matching placebo twice daily for six weeks
Design
RCT, randomised crossover, double-blind
Follow-up
6 weeks per treatment phase
Authors
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Does not support this supplement for BP lowering; confirms null effect on 24-hour ambulatory BP in RCT.
RCT (n=37)
Double-blind
Minimisation method (age, gender and BMI)
No
Does a combined extract of olive leaf, green coffee bean, and beetroot reduce blood pressure in adults with untreated high normal or borderline elevated blood pressure?
Mean Difference: 1.78
Absolute Event Rate: 134.6% vs 132.8%
p-value: p=0.138
A combination of olive leaf, green coffee bean, and beetroot extracts did not lower blood pressure or improve cardiometabolic markers in adults with borderline elevated blood pressure.
Wong et al. (2014) conducted an RCT in Untreated high normal or borderline elevated blood pressure (n=37). Combined extracts of olive leaf, green coffee bean and beetroot vs. Placebo was evaluated on 24-h ambulatory systolic blood pressure (MD 1.78, p=0.138). Six weeks of daily supplementation with a combined formulation of olive leaf, green coffee bean, and beetroot extracts did not significantly lower 24-hour ambulatory blood pressure compared to placebo.
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