Key result
On-X aortic valves match SJM Regent early hemodynamics, lowering peak gradients only in 25 mm sizes.
Why the study?
Does the On-X mechanical aortic valve prosthesis improve early haemodynamics compared to the St Jude Medical Regent prosthesis in patients undergoing aortic valve replacement?
Cohort (n=66)
Yes
Does the On-X mechanical aortic valve prosthesis improve early haemodynamics compared to the St Jude Medical Regent prosthesis in patients undergoing aortic valve replacement?
The On-X and St Jude Medical Regent mechanical aortic valves demonstrate comparable early postoperative haemodynamic performance.
Comparable early performance should not yet change valve selection; leaves open need for randomized long-term comparisons.
OBJECTIVE: We aimed to compare the early haemodynamic data of the On-X and St Jude Medical (SJM) Regent bileaflet mechanical prostheses in the aortic position. METHODS: A retrospective study was performed using data collected prospectively for a national database. Thirty-three patients who had aortic On-X valve (On-X group) and 33 matched patients who had aortic SJM Regent valve (SJM group) were included. The intraoperative and early postoperative data were collected. The same echocardiographer reviewed all the echocardiograms and obtained the required parameters. RESULTS: The peak gradient across the prosthetic valve was comparable between the two groups except for the labelled valve size of 25 mm for which the On-X group had lower peak gradient when compared with the SJM group. Mean gradients and effective orifice area indices of the two valve types within each valve size subgroup were comparable. CONCLUSIONS: The current study confirms that in the early postoperative period, the two valve types had comparable haemodynamic outcomes.
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Xu et al. (2017) conducted a cohort in Aortic valve replacement (n=66). On-X mechanical aortic valve prosthesis vs. St Jude Medical (SJM) Regent mechanical aortic valve prosthesis was evaluated on Early haemodynamic data (peak gradient, mean gradient, and effective orifice area indices). On-X mechanical aortic valve prostheses demonstrated comparable early postoperative haemodynamic outcomes to St Jude Medical Regent valves, with lower peak gradients only in the 25 mm valve size.
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