What question did this study set out to answer?

To establish a mild and efficient nickel-catalyzed electrochemical platform for forming carbon-phosphorus bonds from aryl bromides at room temperature.

August 22, 2019Organic Letters

Nickel-Catalyzed Electrochemical Phosphorylation of Aryl Bromides

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Authors

YBYa Mei BaiNational Yang Ming Chiao Tung University NLNian LiuKunming University of Science and Technology SWShutao WangJilin University

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Implication

Experimental study demonstrates nickel-catalyzed electrochemical phosphorylation of aryl bromides, indicating a sustainable route for carbon-phosphorus bond synthesis.

Key Points

To establish a mild and efficient nickel-catalyzed electrochemical platform for forming carbon-phosphorus bonds from aryl bromides at room temperature.
Conducted electrochemical cross-coupling using an undivided reaction cell paired with low-cost carbon electrodes.
Reacted aryl bromides with diverse organophosphorus precursors, including dialkyl phosphites, ethyl phenylphosphinate, and diphenylphosphine oxide.
Enabled direct carbon-phosphorus bond formation to synthesize aryl phosphonates, aryl phosphinates, and arylphosphine oxides.
Achieved moderate to high product yields under ambient conditions across a broad range of substrates.

Cite This Study

Bai et al. (2019) studied this question.

synapsesocial.com/papers/6aa7e5bb394eb5723c8dab78 https://doi.org/10.1021/acs.orglett.9b02475

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Implication

Experimental study demonstrates nickel-catalyzed electrochemical phosphorylation of aryl bromides, indicating a sustainable route for carbon-phosphorus bond synthesis.

Nickel-Catalyzed Electrochemical Phosphorylation of Aryl Bromides

Discussion

Member takes

Implication

Key Points

Cite This Study

Nickel-Catalyzed Electrochemical Phosphorylation of Aryl Bromides

Discussion

Member takes

Implication

Key Points

Cite This Study

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