Key result
Arterial aging and chronic exposure to cardiovascular risk factors accelerate age-associated arterial burden, contributing to late-life cognitive and depressive disorders.
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The paper highlights the impact of arterial aging and cardiovascular risk factors on the development of late-life depressive and cognitive disorders, raising the question of preventive strategies.
Arterial aging is a dynamic and systemic process characterized by structural and functional changes of blood vessels that exceed the physiological adaptations of the arteries over time. The chronic exposure to cardiovascular (CV) risk factors dramatically accelerates age-associated arterial burden. In Western countries, diabetes mellitus and metabolic syndrome (MetS) have mounted to epidemic proportions, particularly in the older population.[1] Cognitive and depressive disorders are among the leading conditions causing disability in older individuals, as either are tightly associated with decreased quality of life, deterioration in daily living activities, social relationships reduction, sleep disorders and poorer medical outcomes.
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Viscogliosi et al. (2014) conducted an editorial in Arterial aging, cognitive and depressive disorders. Arterial aging and cardiovascular risk factors was evaluated. Arterial aging and chronic exposure to cardiovascular risk factors accelerate age-associated arterial burden, contributing to late-life cognitive and depressive disorders.
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