Key result
Breast cancer radiation improves survival but increases CV mortality risk including CAD.
Why the study?
What are the cardiac complications associated with radiation therapy in breast cancer patients?
What are the cardiac complications associated with radiation therapy in breast cancer patients?
This review highlights the importance of monitoring for radiation-induced coronary artery disease in breast cancer survivors.
Warrants cardiac risk consideration during breast radiotherapy planning; confirms mortality trade-off but leaves optimal mitigation open.
Recent advancements in curative-intent therapies have led to dramatic improvements in breast cancer-specific mortality but at the direct expense of increased risk of cardiovascular-related mortality. The use of radiation therapy has led to significant improvements in survival for patients treated for breast cancer. However, as patients live longer, the potentially serious adverse effects of radiation on the heart have raised concerns. Coronary artery disease following irradiation is encountered rarely but is one of the most devastating treatable complications.In this article we review the cardiac complications associated with radiation therapy.
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Celık et al. (2009) conducted a review in Breast cancer and radiation-induced coronary artery disease. Radiation therapy was evaluated. Radiation therapy for breast cancer improves survival but increases the risk of cardiovascular-related mortality, including rare but devastating coronary artery disease.
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