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November 3, 2020Clinical NeurophysiologyOpen Access

Are early measured resting-state EEG parameters predictive for upper limb motor impairment six months poststroke?

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Key result

Higher early poststroke BSItheta linked to worse upper limb motor impairment at six months.

  • β = -0.40
  • P=0.013
  • n=39

Why the study?

To investigate whether resting-state EEG parameters recorded early poststroke predict upper extremity motor impairment at six months, and whether they add prognostic value to baseline Fugl-Meyer motor scores.

Do early resting-state EEG parameters predict upper limb motor impairment six months poststroke in adults with first-ever ischemic hemispheric stroke?

Population

39 adults within three weeks after a first-ever ischemic hemispheric stroke

Comparison

Early quantitative resting-state EEG parameters evaluated for prognostic value

Design

Cohort study

Follow-up

26 weeks

Authors

MSMique SaesCMCarel G. M. MeskersADAndreas Daffertshofer

Discussion

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Overview

BSItheta may aid early upper limb prognosis poststroke; hypothesis-generating and requires prospective validation before clinical adoption.

Study Design

Type

Cohort (n=39)

Structured PICO

Do early resting-state EEG parameters predict upper limb motor impairment six months poststroke in adults with first-ever ischemic hemispheric stroke?

P
Population
39 adults within three weeks after a first-ever ischemic hemispheric stroke, followed for 26 weeks.
E
Exposure
Resting-state EEG parameters (delta/alpha ratio, brain symmetry index, and directional BSI) recorded early poststroke
O
Outcome
Upper extremity motor impairment reflected by the Fugl-Meyer motor score (FM-UE) at 26 weeks poststroke

Main Result

Effect estimate: β = -0.40

p-value: p=0.013

Early resting-state EEG parameters, specifically BSItheta, provide additive prognostic value to baseline clinical scores for predicting upper extremity motor recovery six months poststroke.

Cite This Study

Saes et al. (2020) conducted a cohort in First-ever ischemic hemispheric stroke (n=39). Resting-state EEG parameters (BSItheta) was evaluated on Upper extremity motor impairment reflected by the Fugl-Meyer motor score (FM-UE) at 26 weeks poststroke (β = -0.40, p=0.013). Higher brain symmetry index over the theta band (BSItheta) early poststroke predicted worse upper limb motor impairment at six months (β = -0.40; p = 0.013).

synapsesocial.com/papers/6aa7f98dff0084718cb187e9https://doi.org/10.1016/j.clinph.2020.09.031
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comments for Current Interpretation EEG Alpha Activity: A Review and Analysis2012 · 40 citations
  2. 2Do movement-related beta oscillations change after stroke?2014 · 150 citations
  3. 3THE RESTORATION OF MOTOR FUNCTION FOLLOWING HEMIPLEGIA IN MAN1951 · 948 citations
  4. 4The Fugl-Meyer Assessment of Motor Recovery after Stroke: A Critical Review of Its Measurement Properties2002 · 2,077 citations