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September 17, 2008Proceedings of the National Academy of SciencesOpen Access

Proteins with weakly funneled energy landscapes challenge the classical structure–function paradigm

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Key result

Proteins with weakly funneled energy landscapes challenge the classical structure-function paradigm.

Design

Other

Authors

GPGaregin A. PapoianOrigin Energy (Australia)

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Implication

May prompt reevaluation of structure-based targeting in cardiac proteins; leaves open functional consequences in disease models.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Garegin A. Papoian (2008) studied this question. Proteins with weakly funneled energy landscapes challenge the classical structure-function paradigm.

synapsesocial.com/papers/6aa8055c1a27575409ae5bf6https://doi.org/10.1073/pnas.0807977105
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