Key result
Canine sick sinus syndrome and chronic mitral valve disease are linked to altered short-term HRV.
Why the study?
Does short-term heart rate variability differ between dogs with sick sinus syndrome or chronic mitral valve disease and healthy controls?
Cross-Sectional (n=90)
No
Does short-term heart rate variability differ between dogs with sick sinus syndrome or chronic mitral valve disease and healthy controls?
Short-term heart rate variability analysis from 60-minute ECGs can help identify sick sinus syndrome and detect dysautonomia in dogs with chronic mitral valve disease.
Short-term HRV differs in dogs with sick sinus syndrome or mitral valve disease; hypothesis-generating and requires prospective validation before clinical use.
Heart rate variability is an established risk factor for mortality in both healthy dogs and animals with heart failure. The aim of this study was to compare short-term heart rate variability (ST-HRV) parameters from 60-min electrocardiograms in dogs with sick sinus syndrome (SSS, n=20) or chronic mitral valve disease (CMVD, n=20) and healthy controls (n=50), and to verify the clinical application of ST-HRV analysis. The study groups differed significantly in terms of both time - and frequency- domain ST-HRV parameters. In the case of dogs with SSS and healthy controls, particularly evident differences pertained to HRV parameters linked directly to the variability of R-R intervals. Lower values of standard deviation of all R-R intervals (SDNN), standard deviation of the averaged R-R intervals for all 5-min segments (SDANN), mean of the standard deviations of all R-R intervals for all 5-min segments (SDNNI) and percentage of successive R-R intervals >50 ms (pNN50) corresponded to a decrease in parasympathetic regulation of heart rate in dogs with CMVD. These findings imply that ST-HRV may be useful for the identification of dogs with SSS and for detection of dysautonomia in animals with CMVD.
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Bogucki et al. (2017) conducted a cross-sectional in Sick sinus syndrome (SSS) and chronic mitral valve disease (CMVD) (n=90). Sick sinus syndrome or chronic mitral valve disease vs. Healthy controls was evaluated on Short-term heart rate variability (ST-HRV) parameters, including SDNN. Compared to healthy controls (SDNN 208.86 ms), short-term heart rate variability was significantly altered in dogs with sick sinus syndrome (SDNN 378.16 ms) and chronic mitral valve disease (SDNN 138.2 ms).
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