Key result
STEMI admissions during the 2021 pandemic return to pre-pandemic levels.
Why the study?
Does the ongoing COVID-19 pandemic (2021) affect admissions, invasive procedures, and mortality in STEMI patients compared to the pre-pandemic period (2019)?
Observational (n=451)
No
Does the ongoing COVID-19 pandemic (2021) affect admissions, invasive procedures, and mortality in STEMI patients compared to the pre-pandemic period (2019)?
Relative Risk: 1.07 (95% CI 0.9–1.28)
p-value: p=0.271
STEMI admissions, invasive procedures, and in-hospital mortality returned to pre-pandemic levels during the ongoing COVID-19 pandemic in 2021 in Albania.
May reassure on STEMI care resilience in 2021; leaves open generalizability and durability beyond this single-center cohort.
, the corresponding period of 2020 total lockdown, for years 2019 and 2021. The control period was considered the year 2019 [pre-pandemic (PP)] and the study period was in 2021 [ongoing pandemic (OP)]. The incidence rate ratio (IRR) 95% confidence interval (CI) was used to compare all-STEMI admissions, invasive procedures, and risk ratio (RR) 95% CI to compare the mortality and complications rate between the study and control period. Results The study included 217 STEMI patients admitted in 2019, and 234 patients during the 2021 period. The overall-STEMI admissions IRR is in a similar range during the 2021 OP compared to the 2019 PP period IRR=1.07 (95%CI 0.90-1.28). Similar invasive procedures were observed during OP compared to PP period, respectively for coronary-angiography IRR= 1.07; (0.87-1.31), for all-PCI [1.12 (0.92-1.35)], and primary percutaneous coronary interventions (PCI) [1.09 (0.89-1.34)]. The STEMI death rate during OP compared to PP period was similar (7.3 vs. 7.4%), RR=1.01 (0.53-1.96), and a non-significant lower primary-PCI-death rate (4.0 vs 4.8%), RR= 0.83 (0.30-2.3)]. Conclusions After the initial reduction of admissions and invasive procedures in STEMI patients during the 2020 lockdown period and the increase of all-STEMI mortality, the number of hospitalizations, invasive procedures, and mortality returned to a similar range during OP compared to the PP period despite a highly incident ongoing COVID-19 pandemic.
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Simoni et al. (2022) conducted an observational in ST-Elevation Myocardial Infarction (STEMI) (n=451). Ongoing COVID-19 pandemic period (2021) vs. Pre-pandemic period (2019) was evaluated on Overall STEMI admissions (IRR 1.07, 95% CI 0.90-1.28, p=0.271). During the ongoing COVID-19 pandemic in 2021, STEMI admissions returned to pre-pandemic levels with an incidence rate ratio of 1.07 compared to 2019.
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