All articles of this category Some 2-substituted methyl 1,3-oxazole-4-carboxylates ( 5 ) can be obtained by the one-step cyclization of N -acylserines ( 3 ) by the combined use of diphenyl sulfoxide and trifluoroacetic anhydride, and subsequent nickel peroxide oxidation of the oxazoline.
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Yokokawa et al. (1992) studied this question.