Key result
MRI detects ~6-fold more brain lesions than CT in patients with infective endocarditis.
Why the study?
Imaging brain involvement in infective endocarditis guides clinical management, but the relative lesion detection rates of readily available CT versus sensitive MRI required direct comparison.
Does MRI improve the detection of brain lesions compared to CT in patients with infective endocarditis?
Population
20 patients who underwent CT and MRI before or after cardiac surgery for definite infective endocarditis
Comparison
Brain MRI vs brain CT
Design
Retrospective study
Authors
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MRI may enhance brain lesion detection versus CT in infective endocarditis; leaves open effects on management and outcomes.
Observational (n=20)
Single-blind
No
Does MRI improve the detection of brain lesions compared to CT in patients with infective endocarditis?
Absolute Event Rate: 162% vs 29%
p-value: p=<0.001
MRI is significantly more sensitive than CT for detecting the full spectrum of brain lesions, including small ischemic lesions and microbleeds, in patients with infective endocarditis.
Vitali et al. (2021) conducted an observational in Infective endocarditis (n=20). MRI vs. CT was evaluated on Detection of brain lesions (p=<0.001). MRI detected significantly more brain lesions than CT in patients with infective endocarditis, identifying 162 of 166 total lesions compared to 29 detected by CT (p < 0.001).
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