Key result
AFM force-distance inversion accuracy depends inherently on sampling frequency, experiment length, and strain rate.
Why the study?
The physical sensibility of parameters from force-distance experiments cannot be assessed, risking falsely attributing physical phenomena to artifacts of violated restrictions.
Demonstrates how to use information theory restrictions to better design AFM force-distance experiments for targeting specific timescales of a material's behavior.
, the physical sensibility of these parameters cannot be assessed and may lead to falsely attributing a physical phenomenon to an artifact of the violation of these restrictions. We use arguments from information theory to understand the nature of these inconsistencies as well as devise limits on the range of mechanical parameters which can be reliably obtained from FD experiments. The results further demonstrate that the nature of these restrictions depends on the domain (time or frequency) used in the inversion process, with the time domain being far more restrictive than the frequency domain. Finally, we demonstrate how to use these restrictions to better design FD experiments to target specific timescales of a material's behaviour through our analysis of a polydimethylsiloxane (PDMS) polymer sample.
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McCraw et al. (2022) studied this question. Atomic Force Microscopy force-distance experiments was evaluated. The range of time-dependent behavior reliably resolved from AFM force-distance inversion is inherently restricted by sampling frequency, experiment length, and strain rate.
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