Key result
Left atrial and coronary sinus RF ablation for WPW linked to myocardial injury and pericarditis.
Why the study?
Radiofrequency catheter ablation is established for Wolff-Parkinson-White syndrome, but rare complications associated with the coronary sinus still occur and remain challenging to identify and avoid.
Does combined left atrial and coronary sinus ablation cause myocardial injury and pericarditis in a patient with WPW syndrome?
Case Report (n=1)
No
Does combined left atrial and coronary sinus ablation cause myocardial injury and pericarditis in a patient with WPW syndrome?
Combined left atrial and coronary sinus ablation for WPW syndrome can cause myocardial injury and pericarditis, highlighting the need for careful ablation with low energy.
May warrant caution with combined LA-CS ablation in WPW; case report leaves open optimal energy settings.
BACKGROUND: Radiofrequency catheter ablation is an established procedure with a high success rate for treating Wolff-Parkinson-White (WPW) syndrome. Rare complications post-ablation may nonetheless occur particularly associated with coronary sinus. Identifying and avoiding these complications remains a challenge. CASE PRESENTATION: A 66-year-old woman with WPW syndrome was admitted to the hospital due to frequent attacks of paroxysmal tachycardia. During electrophysiological study, an accessory pathway was thought to connect the posterior wall of the left ventricle. The patient underwent Radiofrequency (RF) catheter ablation. The procedure was time-consuming because of combined left atrial and coronary sinus ablation. The total amount of radiofrequency application energy in the coronary sinus was 6800 J. After the operation, widespread concave ST-segment elevation, significantly increased value of serum troponin I and mild pericardial effusion were identified, but the patient did not show any symptoms. Therefore, the patient was suspected to have myocardial injury and pericarditis caused by ablation-related injury. The patient was uneventfully discharged five days after the procedure with a significantly decreased value of troponin I. The reexamined electrocardiogram was normal after three weeks. CONCLUSIONS: To the best of our knowledge, this is the first study to report on myocardial injury and pericarditis after combined left atrial and coronary sinus ablation in WPW syndrome. Our findings underscore the need for detailed mapping and careful ablation with low energy, as well as the merits of identifying myocardial infarction after coronary sinus ablation.
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Zheng et al. (2020) conducted a case report in Wolff-Parkinson-White syndrome (n=1). Combined left atrial and coronary sinus radiofrequency catheter ablation was evaluated on Myocardial injury and pericarditis. Combined left atrial and coronary sinus radiofrequency catheter ablation in a patient with Wolff-Parkinson-White syndrome caused myocardial injury and pericarditis.
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