Key result
V4R ST-elevation in anterior MI is linked to a ~110% higher rate of LVEF <40%.
Why the study?
The link between ST-segment elevation in lead V4R and the location and severity of coronary involvement in patients with anterior myocardial infarction remains uncertain.
Does ST-segment elevation in the V4R lead predict lower LVEF and proximal LAD involvement in patients with anterior myocardial infarction?
Observational (n=195)
Does ST-segment elevation in the V4R lead predict lower LVEF and proximal LAD involvement in patients with anterior myocardial infarction?
Absolute Event Rate: 74% vs 35.2%
In patients with anterior myocardial infarction, ST-segment elevation in the V4R lead is associated with a higher likelihood of proximal LAD involvement and significantly lower LVEF.
V4R STE in anterior MI was associated with proximal LAD lesions and lower LVEF; hypothesis-generating for incremental prognostic value.
BACKGROUND: There is some evidence of the association between ST-segment elevation in the V4R chest lead and the likelihood of anterior wall myocardial infarction; however, the link of this phenomenon with the location and the severity of the coronary involvements in such patients remains uncertain. We aimed to investigate the ST-segment elevation in V4R leads in patients with anterior myocardial infarction and also its effect on prognosis as well as the detection and prediction of the location of arterial stenosis in coronary angiography. METHODS: Data collection was performed by reviewing the hospital recorded files of 195 patients' suspicion of acute myocardial infarction who have been referred within 2 h of the onset of cardiac symptoms. The patients were then categorized into two groups with and without ST elevation in the V4R chest lead. RESULTS: lead in those with ST-segment elevation in V4R. Echocardiography on the day after anterior myocardial infarction showed LVEF <40% in 74% and 35.2% of patients with and without ST-segment elevation in V4R, respectively, indicating a significant difference. The lesions on proximal LAD were more common in the group with ST-segment elevation in V4R. CONCLUSION: lead. Also, the appearance of ST-segment elevation in V4R lead can be accompanied with a lower LVEF, myocardial infarct size, involvement of proximal part of LAD, and Wrap around LAD.
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Dehghani et al. (2021) conducted an observational in Anterior myocardial infarction (n=195). ST-segment elevation in V4R lead vs. Without ST-segment elevation in V4R lead was evaluated on LVEF <40% on the day after anterior myocardial infarction. ST-segment elevation in the V4R lead in patients with anterior myocardial infarction was associated with a higher rate of LVEF <40% compared to those without (74% vs 35.2%).
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