Key result
Severe hand, foot and mouth disease predominantly affected rural boys and was primarily caused by EV71, with frequent neurological complications.
Why the study?
Severe HFMD cases predominantly affect boys in rural areas with complications such as aseptic meningitis and encephalitis, but detailed data on these cases were needed.
Answers are grounded in this paper and cite their sources.
EV71 is the dominant etiology for severe and fatal HFMD cases, which predominantly affect boys in rural areas and frequently present with neurological complications.
Most severe HFMD cases appeared in boys, especially living in the rural areas. Frequently seen complications would include aseptic meningitis, non-brainstem encephalitis and brainstem encephalitis. EV71 was the dominant etiology for severe and fatal cases. Early diagnosis and complication control were crucial, related to the treatment outcome of HFMD.
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Zheng et al. (2017) studied this question. Severe hand, foot and mouth disease predominantly affected rural boys and was primarily caused by EV71, with frequent neurological complications.
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