Severe HFMD predominantly affects children under 2 years of age and carries a high case-fatality rate, highlighting the need for early diagnosis and intervention.
Alerts clinicians to severe HFMD in young children; leaves open optimal EV71-specific strategies.
Objective To explore the clinical diagnosis and experiences of treatment of severe patients with HFMD in order to understand HFMD better and accumulate more experience of preventing and treating this disease. Methods Clinical data and treatment of the 68 cases of severe HFMD were analyzed retrospectively. Results In 68 severe cases of HFMD, 58 cases happened children with 2 years lower, fever 61 cases and efflorescence 68 cases (100%). WBC increase in 50 cases rose. AST, CK, CK-MB, LDH and Glu inrease partial cases. Neurogenic pulmonary edema(NPE)and circulation failure could occur on the cases with CNS injure. In 68 cases, 23 cases were EV71-positive, 2 cases were CoxA16-positive, 18 cases were other enterovirus-positive. Treatment of critical cases was difficult, case-fatality rate was high as 2.94%.Conclusions Severe HFMD mostly happened to the children with 2 years lower. Improving diagnosis consciousness and early intervention therapy are critical in reducing the fatality.
No takes yet. Share an insight, caveat, or question.
You et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: