Key result
Severe EV71 hand-foot-and-mouth disease pathogenesis and clinical management remain controversial and poorly understood.
Why the study?
The pathogenesis of severe HFMD caused by EV71 has not been clearly defined and clinical treatment remains controversial, necessitating further exploration of mechanisms and new prevention methods.
Highlights the need for further exploration of the pathogenesis and treatment of severe hand, foot and mouth disease caused by Enterovirus 71 in children.
Unclear EV71 hand-foot-mouth disease pathogenesis warrants cautious management; leaves open key questions on mechanisms and therapies.
The severe hand, foot and mouth disease(HFMD) caused by Enterovirus 71 (EV71) has become a serious threat to children′s health.It is an important issues which need to be faced and resolved by pediatrician and di-sease prevention and control system, especially pediatric critical care specialist.The pathogenesis of severe HFMD caused by EV71 has not been clearly defined so far, and the clinical treatment is controversial.So, to further explore the mechanism of EV71 infection in severe HFMD and explore new effective prevention and control methods, have important significance in reducing the mortality and improve the quality of life of patients with severe HFMD.
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Huiling Deng (2016) conducted a review in Severe hand, foot and mouth disease (HFMD) caused by Enterovirus 71 (EV71). The pathogenesis of severe hand, foot and mouth disease caused by Enterovirus 71 remains unclear and clinical treatment is controversial, highlighting the need for further research.
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