Key result
Review details the pathogenesis, clinical features, and treatment of pulmonary complications in EV71-induced HFMD.
This review summarizes the clinical manifestations, pathogenesis, pathology, imaging changes, and treatment of pulmonary complications associated with EV71-induced hand-foot-mouth disease.
Does not change HFMD management; leaves open prospective validation of EV71 pulmonary imaging findings.
Hand–foot–mouth disease (HFMD) was an acute intestinal infectious disease, which mainly occurred in the children, especially under 5 years old. Enterovirus 71 (EV71) was the most common pathogen causing HFMD, especially severe HFMD. Most patients had a good prognosis, but a few patients complicated by encephalitis, pulmonary edema, and hemorrhage, myocarditis and other complications, which may cause bad prognosis and even death. In this paper, the clinical manifestations, pathogenesis, pathology, imaging changes and treatment of pulmonary inflammation, edema and hemorrhage associated EV71- induced HFMD were reviewed.
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Li et al. (2017) conducted a review in Hand-foot-mouth disease (HFMD) with pulmonary complications. Enterovirus 71 (EV71) infection was evaluated. This review summarizes the clinical manifestations, pathogenesis, pathology, imaging changes, and treatment of pulmonary inflammation, edema, and hemorrhage associated with EV71-induced HFMD.
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