Key result
Percutaneous coronary intervention was associated with elevated inflammatory factors, which correlated with the severity of coronary atherosclerosis and may affect forward arterial blood flow.
Why the study?
Inflammatory reactions caused by vascular wall injury after PCI can affect therapeutic efficacy and rehabilitation in coronary heart disease.
RCT (n=54)
Randomized
In order to prevent the inflammatory reaction caused by vascular wall injury after percutaneous coronary intervention treatment, affecting the therapeutic effect and rehabilitation, this study will select 54 patients with coronary heart disease and then randomly divided them into two groups to observe and compare inflammatory factors and their connection with postoperative thrombolysis in myocardial infarction frame count, the factors include interleukin-6, interleukin-9, interleukin-17A. It has been found that part of factors was elevated after surgery of elective percutaneous coronary intervention for stable coronary heart disease patients, suggesting that percutaneous coronary intervention may induce inflammatory reactions. High level of local inflammatory factors interleukin-6, helper T cells 17 may affect the forward arterial blood flow after interventional intervention. Thrombus aspiration can reduce the occurrence of slow or no reflow in patients with thrombotic load, increase coronary perfusion, improve postoperative cardiac function, and is expected to reduce heart attacks. In patients with coronary heart disease, the expression of inflammatory factors increases with the severity of coronary heart disease and the severity of coronary atherosclerosis. The level of inflammatory factors is correlated with the degree of coronary artery disease, which may promote the progression of coronary lesions. Rehabilitation therapy of traditional Chinese and Western medicine is necessary for patients with coronary heart disease after percutaneous coronary intervention. Active rehabilitation therapy is of great significance in improving the patient’s exercise tolerance, reducing the incidence of cardiovascular adverse events, reducing complications and improving patient’s quality of life.
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Ni et al. (2021) conducted an RCT in Coronary heart disease (n=54). Percutaneous coronary intervention was associated with elevated inflammatory factors, which correlated with the severity of coronary atherosclerosis and may affect forward arterial blood flow.
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