Natural Course of Cytologically Diagnosed Benign Thyroid Nodules

Thyroid nodules are very common and fine needle aspiration is an accurate and cost effective diagnostic tool for differentiating malignant and benign thyroid nodules.Benign diagnosis on cytology is accurate and reliable, however, follow up sonography or fine needle aspiration is recommended to rule out malignancy.Until now, there are few studies regarding natural course of cytologically diagnosed benign thyroid nodules.In this review, malignant risk and long-term follow up data of cytologically diagnosed benign thyroid nodules is discussed.