Key result
Appropriate therapy achieves spectacular remission in a young woman with severe Churg-Strauss acute myocarditis.
Case Report (n=1)
This case highlights that Churg-Strauss syndrome can present initially with severe acute eosinophilic myocarditis and coronary vasculitis, which can be successfully treated with appropriate therapy.
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Supports EGPA evaluation in unexplained myocarditis; hypothesis-generating and should not yet change practice.
Churg-Strauss syndrome (CSS) is an unusual disease that presents as systemic vasculitis and peripheral eosinophilia in patients with an atopic constitution. Cardiac involvement is unusual and often not prominent on initial presentation, but is an important cause of morbidity and mortality in patients with CSS. We report the case of a young woman with severe acute myocarditis. Coronary arteriography demonstrated extensive focal vasculopathy, consistent with coronary vasculitis, and myocardial biopsy showed eosinophilic myocarditis. This presentation led to an initial diagnosis of CSS in this patient and appropriate therapy resulted in a spectacular remission of disease activity.
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Correia et al. (2013) conducted a case report in Churg-Strauss syndrome with eosinophilic myocarditis (n=1). Appropriate therapy was evaluated on Remission of disease activity. Appropriate therapy resulted in a spectacular remission of disease activity in a young woman presenting with severe acute myocarditis due to Churg-Strauss syndrome.
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